茶对氟化物和呕吐毒素对大鼠肝糖原分解的保护作用

茶对氟化物和呕吐毒素对大鼠肝糖原分解的保护作用
目的  探究茶对氟与呕吐毒素染毒大鼠肝糖原含量降低的保护作用。方法  将50只Wistar大鼠分为空白组、呕吐毒素染毒组、氟染毒组、联合染毒组和饮茶干预组, 染毒5周后解剖大鼠, 用蒽酮比色法试剂盒检测肝糖原含量。结果  氟单独染毒、呕吐毒素与氟联合染毒后肝糖原含量显著性降低(P<0.05), 呕吐毒素与氟联合染毒后的肝糖原含量显著性低于呕吐毒素单独染毒(P<0.05), 饮茶干预后的肝糖原含量显著提高(P<0.05)。结论  呕吐毒素和氟化物对肝糖原有损伤作用, 茶对其损伤有保护性作用。

Objective  To explore the protective effect of tea on the decrease of glycogen content in liver of rats exposed to fluoride and deoxynivalenol. Methods  Fifty Wistar rats were divided into blank group, deoxynivalenol exposure group, fluoride exposure group, combined exposure group and tea drinking intervention group. After 5 weeks of exposure, the rats were dissected and the liver glycogen content was detected by anthrone colorimetry kit. Results  The content of liver glycogen was significantly decreased after exposure to fluoride alone and combined exposure to deoxynivalenol and fluoride (P<0.05). The content of liver glycogen after combined exposure to deoxynivalenol and fluoride was significantly lower than that after exposure to deoxynivalenol alone (P<0.05), and the content of liver glycogen was significantly increased after drinking tea (P<0.05). Conclusion  Deoxynivalenol and fluoride have the effect of reducing liver glycogen. Tea has protective effect on this damage.

标题：茶对氟化物和呕吐毒素对大鼠肝糖原分解的保护作用
英文标题：The protective effect of tea on fluoride and deoxynivalenol on liver glycogen decomposition in rats

作者：
韩景辉 山东第一医科大学(山东省医学科学院)公共卫生学院
任兴葡 山东第一医科大学(山东省医学科学院)公共卫生学院
齐冰 山东第一医科大学(山东省医学科学院)生命科学学院
李群伟 山东第一医科大学(山东省医学科学院)公共卫生学院
安康 山东第一医科大学(山东省医学科学院)公共卫生学院

中文关键词:茶,氟,呕吐毒素,肝糖原,
英文关键词:tea,fluorine,deoxynivalenol,liver glycogen,

发表日期：2020-03-11

2025-2-27 20:36 上传 茶对氟化物和呕吐毒素对大鼠肝糖原分解的保护作用.pdf

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