Campylobacter is a kind of zoonotic pathogen which is widely concerned in the world. It is also one of the main foodborne pathogens causing acute gastroenteritis in humans. Fluoroquinolone is an empirical drug for the clinical treatment of Campylobacter infections. However, excessive use of antibiotics in animal diseases and human medical treatment has led to an increase in resistance to Campylobacter. In recent years, studies on the resistance of Campylobacter to fluoroquinolones have been reported around the world. This paper reviewed the bactericidal mechanism of fluoroquinolones, the present situation of drug resistance of Campylobacter to fluoroquinolones and the mechanism of drug resistance, so as to provide some references for the rational application of fluoroquinolones for Campylobacter.
标题:弯曲菌对氟喹诺酮类抗生素耐药性及耐药机制研究进展
英文标题:Resistance of Campylobacter and its resistance mechanisms to fluoroquinolones