早期肠内营养支持联合个性化口腔护理对舌癌手术预后的影响
目的 探究早期肠内营养支持联合个性化口腔护理对舌癌手术预后的影响。方法 回顾性分析2008年9月至2012年11月我院收治的87例舌癌患者, 患者均进行舌癌根治术治疗。根据术后治疗方案不同将患者分为2组, 其中对照组患者(n=42)于术后进行个性化口腔护理, 研究组患者(n=45)则在此基础上加用早期肠内营养支持治疗。对比2组患者入院与出院时的各项营养指标、生活质量评分、淋巴结转移、3年和5年生存率以及术后并发症等情况。结果 入院时与出院时2组患者的体重水平经比较均无明显差异(P>0.05), 入院时患者的氮平衡、前白蛋白与转铁蛋白水平2组间无明显差异(P>0.05), 但出院时研究组患者的上述各项营养指标水平均优于对照组(P<0.05); 研究组患者的躯体功能、心理功能、社会功能、物质生活等4个维度的评分均明显高于对照组患者(P<0.05); 研究组患者术后各项并发症的总发生率(8.89%)明显低于对照组患者(28.57%), P<0.05, 差异存在统计学意义; 研究组患者的淋巴结转移率(35.56%)明显低于对照组患者(57.14%), 而5年生存率(75.56%)明显高于对照组患者(52.38%), 2组间差异存在统计学意义(P<0.05)。结论 早期肠内营养支持联合个性化口腔护理可有助于改善舌癌患者的术后营养指标和生活质量, 减少并发症, 对降低患者的淋巴结转移率, 提高患者的生存率有显著的意义, 值得临床进一步推广应用。
Objective To investigate the effects of early enteral nutrition support combined with personalized oral care on the prognosis of tongue cancer surgery. Methods A retrospective analysis of 87 cases of tongue cancer patients admitted to Huangshi Central hospital from September 2008 to November 2012, all patients underwent radical cancer treatment. Patients were divided into 2 groups according to the postoperative treatment plan. Patients in the control group (n=42) underwent personalized oral care after surgery, and patients in the study group (n=45) were treated with early enteral nutrition support on the basis of personalized oral care after surgery. The nutritional indicators, quality of life scores, lymph node metastasis, 3-year and 5-year survival rates, and postoperative complications of the 2 groups at admission and discharge were compared. Results There was no significant difference in body weight between the 2 groups at admission and at discharge (P>0.05). There was no significant difference in the nitrogen balance, prealbumin and transferrin levels between the 2 groups at admission (P>0.05), but the above-mentioned nutritional indicators of the study group were better than the control group (P<0.05). The scores of the 4 dimensions of physical function, psychological function, social function and material life of the study group were significantly higher than those of the control group (P<0.05). The total incidence of postoperative complications (8.89%) in the study group was significantly lower than that in the control group (28.57%) (P<0.05), and the difference was statistically significant. The lymph node metastasis rate of the study group (35.56%) was significantly lower than that of the control group (57.14%), while the 5-year survival rate (75.56%) was significantly higher than that of the control group (52.38%). The difference between the 2 groups was statistically significant (P<0.05). Conclusion Early enteral nutrition support combined with personalized oral care can help improving postoperative nutritional status and quality of life in patients with tongue cancer, reducing complications. It has significant significance in reducing the lymph node metastasis rate and improving the survival rate of patients, which is worthy of further clinical application.
标题：早期肠内营养支持联合个性化口腔护理对舌癌手术预后的影响
英文标题：Effect of early enteral nutrition support combined with personalized oral care on prognosis of tongue cancer surgery
作者：
张曦 鄂东医疗集团黄石市中心医院
何代捷 鄂东医疗集团黄石市中心医院
中文关键词:肠内营养,个性化,口腔护理,舌癌,
英文关键词:enteral nutrition,personalization,oral care,tongue cancer,
发表日期：2018-09-06
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