2015~2017年石家庄市畜禽产品中磺胺类兽药残留及风险评估
目的 通过调查2015~2017年石家庄市畜禽产品中磺胺类兽药残留监测并对其进行风险评估, 确定并量化其中磺胺类的膳食摄入风险水平, 为畜产品安全生产、消费及安全监管提供依据。方法 采集1200份畜禽产品样品, 采用高效液相色谱-串联质谱法对样品中磺胺类等兽药残留进行监测, 并结合2015年中国居民膳食调查数据, 使用专业风险评估软件@Risk, 构建非参数概率评估模型, 对石家庄市民食用的畜禽产品中磺胺类兽药的摄入进行风险评估。结果 检测的1200份主要畜禽产品共有8份检出有磺胺类兽药残留, 其残留主要为磺胺二甲嘧啶残留、磺胺间甲氧嘧啶及磺胺间二甲氧嘧啶, 检出率分别为0.17%、0.25%和0.25%, 平均残留浓度分别为0.66、0.50和0.50 μg/kg, 远低于国家残留限量标准100 μg/kg, 而其他磺胺类兽药均未检出。食品安全指数为2.95×10?4, 远小于1。结论 石家庄市居民食入畜禽肉中的磺胺类兽药残留暴露风险很低, 处于非常安全的水平, 但仍需要加强对动物性畜禽产品的监管, 以降低兽药在人体内的残留。
Objective To investigate and assess the risk of sulfonamides residues in livestock and poultry products in Shijiazhuang in 2015-2017, and determine the risk level of the dietary intake of sulfonamides, in order to provide the basis for the safety production, consumption and safety supervision of livestock products. Methods Totally 1200 samples of livestock products were collected and the samples were detected by high performance liquid chromatography-tandem mass spectrometry. Combined with the data of Chinese residents' dietary survey in 2015, a non parametric probability assessment model was constructed to assess the risk of sulfonamides in the livestock and poultry products of Shijiazhuang residents by using the professional risk assessment software @Risk. Risk assessment of the consumption of sulfonamide veterinary drugs in livestock and poultry products of Shijiazhuang residents was conducted. Results Of the 1200 main livestock products tested, 8 were found to have sulfonamides residues, which were mainly sulfadiazine residue, sulfadiazine and sulfadimethoxy, with the detection rates of 0.17%, 0.25% and 0.25%, respectively. The average residual concentrations were 0.66, 0.50 and 0.50 g/kg, respectively, which were lower than the national residue limit of China (100 μg/kg). The food safety index was 2.95×10-4, which was far less than 1. Conclusion The risk of residual exposure to sulfonamides in livestock and poultry meat in Shijiazhuang is very low and is at a very safe level. However, it is still necessary to strengthen the supervision of animal products in order to reduce the residues of veterinary drugs in the human body.
标题：2015~2017年石家庄市畜禽产品中磺胺类兽药残留及风险评估
英文标题：Sulfonamides residues and risk assessment of animal products of 2015-2017 in Shijiazhuang city
作者：
左晓磊 石家庄市畜产品质量监测中心;DepartmentofFoodScienceandTechnology,UniversityofNebraska-Lincoln,LincolnNebraskaUSA
王冰 内布拉斯加大学林肯分校
中文关键词:畜产品,磺胺残留,食品安全指数,风险评估,
英文关键词:animal product,sulfonamides residue,index of food safety,risk assessment.,
发表日期：2018-05-12
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