蔓越莓复合提取物对小鼠免疫功能的影响
目的 评价蔓越莓、越橘、玫瑰茄复合提取物作为保健食品增强免疫力的作用。方法 分别以0.26 、0.52和0.78 g/kg剂量连续灌胃小鼠30 d后, 通过小鼠淋巴细胞转化试验、抗体生成细胞测定、血清溶血素检测、迟发型变态反应、小鼠碳廓清实验、腹腔巨噬细胞吞噬鸡红细胞实验和自然杀伤细胞(natural killer, NK细胞)活性测定等试验, 评价其对小鼠免疫力的影响。结果 蔓越莓、越橘、玫瑰茄复合提取物能促进淋巴细胞转化, 增加抗体生成细胞的数量, 增强NK细胞的活性。结论 蔓越莓、越橘、玫瑰茄复合提取物可以增强小鼠的免疫力。
Objective To evaluate the effects of composite extraction of Oxycoccos, Vaccinium vitis-idaea and Hibiscus sabdariffa on immunity enhancement in mice. Methods The composite extraction (0.26, 052 and 0.78 g/kg) was consistently administered intragastricly for 30 days. Subsequently, immune function indexes including lymphocyte transformation, antibody production cells, serum hemolysin, delayed type hypersensitivity, carbon clearance, phagocytosis of chicken erythrocytes by peritoneal macrophages, and NK (natural killer) cell activity were measured to evaluate the effects of immunity enhancement. Results Under the condition of this experiment, the transformation of spleen lymphocyte was stimulated, the quantity of antibody-producing cells was increased and the activity of natural killer cells was enhanced. Conclusion It is suggested that the composite extraction of Oxycoccos, Vaccinium vitis-idaea and Hibiscus sabdariffa could enhance the immune function of mice.
标题：蔓越莓复合提取物对小鼠免疫功能的影响
英文标题：Effects of composite extraction of Oxycoccos on immunity in mice
作者：
李瑞鹏 广州医药研究总院有限公司药物非临床评价研究中心
欧慧瑜 广州医药研究总院有限公司药物非临床评价研究中心
郭秋平 广州医药研究总院有限公司药物非临床评价研究中心
中文关键词:蔓越莓,越橘,玫瑰茄,免疫力,
英文关键词:Oxycoccos,Vaccinium vitis-idaea,Hibiscus sabdariffa,immunity,
发表日期：2017-07-21
- 文件大小:
- 445.07 KB
- 下载次数:
- 60
-
高速下载
|
|
