Visfatin和A-FABP水平及PPARγ2基因多态性 与心脑血管疾病关系研究进展
目前, 国内外学者通过检测脂肪细胞型脂肪酸结合蛋白(adipocyte fatty acid binding protein, A-FABP)和内脂素(visfatin)水平, 评价其与代谢综合征(metabolic syndrome, MS)的相关性。过氧化物酶体增殖物激活受体(peroxisome proliferator activated receptor gamma 2, PPARγ)可能在肥胖、高血压、脂代谢异常等疾病中发挥着关键作用, 是MS的重要侯选基因。本文综述了Visfatin、A-FABP水平和PPARγ2基因多态性与心脑血管疾病(cardio-cerebrovascular disease)关系的研究进展, 为制定非传染性疾病(non-communicable disease, NCD)预防和控制战略及干预措施提供借鉴。
Scholars at home and abroad have detected lard type fatty acid binding protein (A-FABP) and visfatin level, and evaluated their relevance to the metabolic syndrome (MS). Besides, peroxidase body growth activated receptor (PPARγ) may also play key role in diseases including obesity, high blood pressure, abnormal lipid metabolism, and thus could be one of the important candidate genes of MS. The paper their relationship with cardio-cerebrovascular disease, and provide scientific references for the prevention and control of non-communicable disease (NCD).
标题：Visfatin和A-FABP水平及PPARγ2基因多态性 与心脑血管疾病关系研究进展
英文标题：Research progress on cardio-cerebrovascular disease visfatin, a-fabp, pparγ2 gene polymorphism and their relationships with cardio/cerebrovascular disease
作者：
张正武 昆明医科大学营养与食品研究所
潘红梅 昆明医科大学营养与食品研究所
张丽娟 云南中医学院基础医学院
张雪辉 昆明医科大学营养与食品研究所
殷建忠 昆明医科大学营养与食品研究所
中文关键词:内脂素,脂肪细胞型脂肪酸结合蛋白,氧化物酶体增殖物激活受体,非传染性疾病,
英文关键词:visfatin,adipocyte fatty acid binding protein(A-FABP),peroxisome proliferator activated receptor gamma 2(PPARγ2),non-communicable disease(NCD),
发表日期：2013-09-16
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