GC-MS法研究白油在肉鸡肾脏中残留的动态变化
目的 通过模拟疫苗接种模式研究矿物油在肉鸡肾脏残留的动态变化。 方法 采用矿物油(白油7#)肌肉注射15日龄雏鸡, 运用GC-MS法检测注射后3、7、14、28 d和56 d时鸡肾脏中矿物油成分。结果 3 d后就能在肾脏中检测到10种烷烃组分; 随后能够检测出的烷烃种类有所减少, 但在注射56天时仍能从肾脏中检测出6种烷烃成分。 结论 矿物油会随血液循环到达肾脏, 代谢周期长, 使用矿物油作为佐剂存在残留问题, 有一定的食用安全隐患。
Objective To determine the residues of mineral oil components in the chicken’s kidney and to investigate the metabolic changes of mineral oil components in a simulated vaccination model. Methods Chicken of 15-day-old were injected im with white oil No.7 (a commercially available mineral oil adjuvant) and the residues of oil components in kidney were determined using GC-MS method on the d 3, d 7,d 14 , d 28, and d 56 after injection. Results It was found that on d 3 after the injection, 10 alkanes were detected among the 11 alkanes detected in white oil No.7 in the kidney, and on d 56 after injection there were still 6 alkanes detected in the kidney. Conclusion The results showed that the mineral oil reached the kidney via circulation, and using mineral oil as an adjuvant in food production of animal origin might bring some safety risks.
标题：GC-MS法研究白油在肉鸡肾脏中残留的动态变化
英文标题：Determination of mineral oil residues in chicken's kidney by GC-MS
作者：
刘亮 1.川北医学院实验动物中心;2.西南民族大学
唐善虎 西南民族大学
李阳友 川北医学院实验动物中心
姜艳 川北医学院实验动物中心
中文关键词:肾脏,矿物油,GC-MS,残留,食品安全,
英文关键词:kidney,mineral oil,gas chromatography-mass spectrometry,residue,food safety,
发表日期：2012-05-23
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